symposium THEme

                Human Genome Project is largely complete, so the problem facing by scientists is how to maximize the use of the newly acquired data for improving health care. It is estimated that the number of therapeutic targets available for drug discovery will increase from the current number of 600 to 1000 to perhaps as many as 5000 to 10,000. In addition to the challenges that this number provides to the pharmaceutical industry, there is the issue of sequence variation through Single Nucleotide Polymorphisms (SNPs), some of which may impact upon the way that the body handles drug treatment. This may be due to a direct effect on the binding site of the protein target through non-conservative alterations of the amino acid sequence, or else through indirect effects on drug metabolizing enzymes. In order to meet these challenges, the combination of structural proteomics and computer-aided small molecule design provides opportunities for creating new molecules in silico; these may be designed to bind to selected pharmacogenetic variants of a protein in order to overcome the non-responsiveness of certain patient groups to a particular medicine. More

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SBCADD-2012 ABSTRACTS & SOUVENIR ( ISBN: 978-93-80243-69-6)

SBCADD-2012 Press Release

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Plenary Speakers
  • Dr. U. Deva Priyakumar
    International Institute of Information Technology, Hyderabad
  • Dr. K. Gunasekaran
    University of Madras, Chennai
  • Dr. J. Jeyakanthan
    Alagappa University, Karaikudi
  • Dr. R. Krishna
    Pondicherry University, Puducherry
  • Dr. S. Krishnaswamy
    Madurai Kamaraj University, Madurai
  • Dr. M. Michael Gromiha
    Indian Institute of Technology, Chennai
  • Dr. S. Parthasarthy
    Bharthidasan University, Trichy
  • Dr. Prasad A. Wadegaonkar
    Sant Gadge Baba Amravati University, Amravati
  • Dr. Ritushree Kukreti
    Institute of Genomics and Integrative Biology, Delhi
  • Dr. Sanjeev Kumar Singh
    Alagappa University, Karaikudi
  • Dr. N. Sundara Baalaji
    Bharathiar University, Coimbatore
  • Dr. Sunil Kumar
    Institute of Life Sciences, Bhubaneswar
  • Dr. M. Suresh Kumar
    Pondicherry University, Puducherry
  • Dr. K. Thangaraj
    Centre for Cellular & Molecular Biology, Hyderabad
  • Dr. D. Velmurugan
    University of Madras, Chennai
  • Mr. R. Raghu
    Schrodinger, USA

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